Having already completed one revenge mission on champions St Helens this season in Round 3, Leeds Rhinos will be looking to pick up another victory over their conquerors in last season's Betfred Super League Grand Final when the two teams meet at Headingley on Friday.
The Old Trafford rematch is just one of four key fixtures taking place, so here is everything you need to know about the evening's slate of action.
Catalans Dragons v Wakefield Trinity
Where: Stade Gilbert Brutus, Perpignan.
When: 6pm (BST), 7pm (local)
TV: No live UK coverage
Catalans' last five: Won 46-22 @ Castleford (Rd 12), Won 24-12 v St Helens (Rd 11), Lost 14-16 @ Salford (Rd 10), Lost 14-26 @ Huddersfield (Rd 9), Lost 14-20 v Warrington (Rd 8)
Wakefield's last five: Lost 6-26 v Hull FC (Rd 12), Lost 18-32 @ Warrington (Rd 11), Lost 6-22 @ Wigan (Rd 10), Lost 0-32 v Leigh (Rd 9), Lost 4-16 @ Castleford (Rd 8)
Betfred match winner odds (80 minutes): Catalans 1/22, Wakefield 9/1, draw 28/1
First try scorer odds: Fouad Yaha (Catalans) 6/1, Tom Johnstone (Catalans) 6/1, Matt Ikuvalu (Catalans) 10/1, Arthur Mourgue (Catalans) 11/1, Mathieu Laguerre (Catalans) 12/1
Trinity's Jay Pitts and Eddie Battye are both one appearance shy of career milestones, with Pitts currently on 349 total games and Battye having so far recorded 249.
Round 1, 2023: Wakefield Trinity 24, Catalans Dragons 38
Round 22, 2022: Wakefield Trinity 16, Catalans Dragons 20
Round 2, 2022: Catalans Dragons 24, Wakefield Trinity 22
Round 16, 2021: Catalans Dragons 40, Wakefield Trinity 20
Round 5, 2021: Wakefield Trinity 18, Catalans Dragons 38
Total Super League meetings: 42 (Catalans 24, Wakefield 18, no draws)
Catalans' season-long battle with injuries continues, with Mitchell Pearce, Sam Tomkins and Manu Ma'u all dropping out from the squad which was beaten by Warrington Wolves in the Betfred Challenge Cup last weekend. Steve McNamara's side have actually won their last two Super League games - including a statement result against champions St Helens - but have some catching up to do having lost four out of five between Rounds 6 and 10.
Wakefield need a win from somewhere. Their run of 12 consecutive losses to start the season remains a long way from the Super League record but they need to arrest their current slide if they are to have any hope of survival. Former Steve Prescott Man of Steel winner Luke Gale is in line to make his Trinity debut, while Max Jowitt returns to the squad and Jack Croft could play for the first time since re-signing Wynnum Manly Seagulls.
Sportsman stat: At the time of writing, St Helens (9/4), Wigan Warriors (11/4), Warrington Wolves (11/4) and Catalans (8/1) are all shorter odds to win the Grand Final than Wakefield are to win (9/1) in Perpignan on Friday night.
Huddersfield Giants v Castleford Tigers
Where: John Smith's Stadium, Huddersfield.
When: 7.45pm (BST)
TV: No live screening
Huddersfield's last five: Lost 4-30 v Leigh (Rd 12), Lost 0-28 @ Hull KR (Rd 11), Lost 14-20 @ Hull FC (Rd 10), Won 26-14 v Catalans (Rd 9), Lost 17-18 @ Leeds (Rd 8)
Castleford's last five: Lost 22-46 v Catalans (Rd 12), Lost 6-30 @ Leigh (Rd 11), Lost 7-12 v Hull KR (Rd 10), Lost 6-14 @ Salford (Rd 9), Won 16-4 v Wakefield (Rd 8)
Betfred match winner odds (80 minutes): Huddersfield 2/11, Castleford 4/1, draw 22/1
First try scorer odds: Jake Bibby (Huddersfield) 9/1, Sam Halsall (Huddersfield) 9/1, Innes Senior (Huddersfield) 10/1, Will Pryce (Huddersfield) 10/1, Esan Marsters (Huddersfield) 10/1
Jermaine McGillvary is a hat-trick away from reaching a career total of 250 tries, with 204 of his 247 to date coming in the colours of Huddersfield Giants.
Elsewhere, Adam O'Brien could make his 150th Super League appearance and Tui Lolohea will reach his century of games in the competition if selected. Sebastine Ikahihifo will be appearing for Huddersfield for the 100th time if he is in the matchday squad.
Round 4, 2023: Huddersfield Giants 36, Castleford Tigers 6
Round 24, 2022: Huddersfield Giants 36, Castleford Tigers 10
Round 17, 2022: Castleford Tigers 26, Huddersfield Giants 18
Round 5, 2022: Huddersfield Giants 36, Castleford Tigers 24
Round 17, 2021: Castleford Tigers 16, Huddersfield Giants 34
Total Super League meetings: 53 (Huddersfield 23, Castleford 30, no draws)
Huddersfield have been one of the biggest letdowns of the Super League season so far, their pre-season promise having given way to unconvincing results and an unappealing style of play. Ian Watson's troops need to find their form sooner rather than later, and they will be expected to get back on the bike against Leigh on Friday.
The Leopards, though, have been one of the positives of the campaign and have strung together three consecutive wins to sit inside the top six after 11 rounds. Adrian Lam has been able to get a tune out of a squad which could easily have taken their foot off the pedal in the face of Wakefield Trinity's horrible form this season, the expectation for promoted side normally being an 11th place finish at best.
Sportsman stat: Huddersfield have won their last three home fixtures against Cas, with the Tigers' last success on the field coming back in 2019 with a 24-0 win. They were awarded a victory of the same scoreline in 2021 when the Giants were blighted by Covid-19 and were forced to forfeit the game as a result.
Leeds Rhinos v St Helens
Where: Headingley Stadium, Leeds.
When: 8.00pm (BST)
TV: Sky Sports Arena
Leeds' last five: Won 40-18 @ Wigan (Rd 12), Lost 12-22 v Salford (Rd 11), Lost 6-20 @ Leigh (Rd 10), Won 34-10 v Hull FC (Rd 9), Won 18-17 v Huddersfield (Rd 8)
St Helens' last five: Won 26-12 v Salford (Rd 12), Lost 12-24 @ Catalans (Rd 11), Won 28-6 v Warrington (Rd 10), Lost 14-26 @ Hull KR (Rd 9), Lost 6-14 @ Wigan (Rd 8)
Betfred match winner odds (80 minutes): Leeds 6/4, St Helens 4/7, draw 18/1
First try scorer odds: Tommy Makinson (St Helens) 7/1, Tee Ritson (St Helens) 8/1, Ash Handley (Leeds) 9/1, Konrad Hurrell (St Helens) 10/1, Jon Bennison (St Helens) 11/1
Richie Myler is one appearance away from reaching 300 in Super League, with Sam Lisone could make his 150th career appearance. On the other side of the field, Tommy Makinson will be appearing for St Helens for the 300th time if selected.
Round 3, 2023: St Helens 24, Leeds Rhinos 25
Grand Final, 2022: St Helens 24, Leeds Rhinos 12
Round 16, 2022: St Helens 42, Leeds Rhinos 12
Round 7, 2022: Leeds Rhinos 0, St Helens 26
Semi-Final, 2021: St Helens 36, Leeds Rhinos 8
Total Super League meetings: 77 (Leeds 33, St Helens 44, no draws)
Leeds have been the epitome of inconsistency so far in 2023, with a string of underwhelming results punctuated with magnificent victories against the likes of St Helens, Catalans Dragons and Wigan Warriors. That 40-18 defeat of Wigan from 14-6 and one man down was one of the performances of this and many a Super League season. They were unable to back it up when they met the Warriors again in the Challenge Cup last week, so they will be desperate to repeat their courageous 25-24 success over the world champions back in Round 3.
Saints have been up and down as well. That World Club Challenge win over Penrith Panthers has come at quite a cost, with the high-intensity beginning to the season falling away to provide for some lacklustre showings. They were good winners over Salford Red Devils in their last Super League game though, and held Halifax Panthers off in the Betfred Challenge Cup. Paul Wellens will be reminding his side how they felt after that narrow loss to Leeds earlier in the season.
Sportsman stat: The last time the Super League champions failed to beat their Grand Final opponents in any of the following season's encounters came back in 2018, when Leeds lost all three fixtures against Castleford, whom they had overcome 24-6 in the '17 showpiece.
Leigh Leopards v Warrington Wolves
Where: Leigh Sports Village, Leigh.
When: 8.00pm (BST)
TV: No live screening
Leigh's last five: Won 30-4 @ Huddersfield (Rd 12), Won 30-6 v Castleford (Rd 11), Won 20-6 v Leeds (Rd 10), Won 32-0 @ Wakefield (Rd 9), Lost 20-22 v Salford (Rd 8)
Warrington's last five: Won 21-14 v Hull KR (Rd 12), Won 32-18 v Wakefield (Rd 11), Lost 6-28 @ St Helens (Rd 10), Lost 6-13 v Wigan (Rd 9), Won 20-14 @ Catalans (Rd 8)
Betfred match winner odds (80 minutes): Leigh 7/5, Warrington 8/13, draw 18/1
First try scorer odds: Josh Charnley (Leigh) 8/1, Matty Ashton (Warrington) 8/1, Matt Dufty (Warrington) 9/1, Matty Russell (Warrington) 11/1, Tom Briscoe (Leigh) 12/1
Warrington's Ben Currie has scored 98 tries in his senior career, including 91 for the Wolves and two for England. The other five were scored on dual registration at Swinton Lions.
Round 5, 2023: Warrington Wolves 38, Leigh Leopards 20
Round 11, 2021: Warrington Wolves 44, Leigh Centurions 18
Round 2, 2021: Warrington Wolves 44, Leigh Centurions 12
Qualifiers Round 5, 2017: Warrington Wolves 32, Leigh Centurions 30
Round 21, 2017: Warrington Wolves 50, Leigh Centurions 10
Total Super League meetings: 7 (Leigh 1, Warrington 6, no draws)
The Leopards are Super League's form club, with four straight top-flight wins being racked up before they gave Wakefield Trinity a pasting in the Betfred Challenge Cup last week. They face a massive challenge against the league leaders though, with tempers likely to be tested after a couple of feisty affairs in Warrington earlier this season, once in the league and once in a friendly match.
Just when Daryl Powell's Wolves looked to be falling away as some critics had predicted, they have bounced back with back-to-back league wins and a cup triumph over Catalans. Heading into Round 13 four points clear, they will have been reminded in training this week about the need to make hay while the sun shines, and anything other than a win on Friday will be considered a let-down, even if Leigh are the most in-form side in the country.
Sportsman stat: Leigh have won only one of the last 18 meetings between the two clubs dating back to 1988.
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